a. action: stabilize leukocyte lysosomal membranes, inhibit phagocytosis and release of allergic substances
b. examples
i. hydrocortisone sodium succinate (Solu-Cortef)
ii. hydrocortisone sodium phosphate (Hydrocortone)
c. use: to suppress inflammatory or immune responses
d. adverse reactions
i. sodium and fluid retention
ii. nausea, acne, impaired wound healing
iii. anaphylactic reaction
iv. masking of infection
v. behavior changes
e. contraindications
i. hypersensitivity
ii. systemic fungal infections
f. nursing interventions
i. establish baseline of vital signs, I/O ratio, weight
ii. monitor blood pressure during stabilization period
iii. assess client's response to treatment
iv. teach client
• take oral steroid with food
• take anti-inflammatories on schedule and don't stop abruptly
• expect a slight weight gain
• avoid alcohol and caffeine
• do not use OTC medications unless approved by health care provider
• report slow healing, vague feeling of being sick, or relapse
• use medic alert jewelry or ID
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